Peptidoglycan Atlas

Akkermansia muciniphila

Open unified details / 打开统一详情 / Abrir detalles

Akkermansia muciniphila

Recorded chemistry / 记录的化学组成 / Química registrada

mDAP-type stems. MucT contains non-acetylated GlcN and O-acetylated MurNAc variants.

Recorded evidence / 已记录证据 / Evidencia registrada

Chemical characterization of MucT (ATCC BAA-835) and later LC-MS/MS profiling support modified glycan-bearing muropeptides.

Limitations / 局限 / Limitaciones

Keep preparation-specific proportions separate. Modified glycans must not be silently replaced by unmodified GlcNAc–MurNAc. A complete peak and bond map is not yet curated.

Akkermansia muciniphila

Recorded chemistry / 记录的化学组成 / Química registrada

mDAP 型肽干。MucT 检出未乙酰化 GlcN 和 O-乙酰化 MurNAc 变体。

Recorded evidence / 已记录证据 / Evidencia registrada

MucT（ATCC BAA-835）的化学鉴定及后续 LC-MS/MS 分析支持这些带修饰糖链的胞壁肽。

Limitations / 局限 / Limitaciones

不同样品的比例应分别保留，不能把修饰糖默认为未修饰 GlcNAc–MurNAc；完整逐峰、逐键图尚未整理。

Akkermansia muciniphila

Recorded chemistry / 记录的化学组成 / Química registrada

Tallos de tipo mDAP. MucT contiene variantes con GlcN no acetilada y MurNAc O-acetilado.

Recorded evidence / 已记录证据 / Evidencia registrada

La caracterización química de MucT (ATCC BAA-835) y perfiles posteriores por LC-MS/MS respaldan muropéptidos con glicanos modificados.

Limitations / 局限 / Limitaciones

Mantener separadas las proporciones de cada preparación. No sustituir los glicanos modificados por GlcNAc–MurNAc sin modificar. Falta un mapa completo de picos y enlaces.

Sources / 来源 / Fuentes

  1. Peptidoglycan from Akkermansia muciniphila MucT: chemical structure and immunostimulatory properties of muropeptides

    Access / 访问 / Acceso: abstract

    Locator / 定位 / Localización: Author institution abstract: strain MucT/ATCC BAA-835 and sugar modifications; full article not inspected in this audit.

  2. In silico MS/MS prediction for peptidoglycan profiling uncovers novel anti-inflammatory peptidoglycan fragments of the gut microbiota

    Access / 访问 / Acceso: full_text

    Locator / 定位 / Localización: Results: comprehensive PGN profiling in gut bacteria; Figures 4B and 5.