Bifidobacterium adolescentis

Lys-rich, not exclusively Lys: Orn variants coexist. The Lys subgroup has β-Asp/β-isoAsn bridges and abundant anhydro-MurNAc.

LC-MS/MS resolves heterogeneous stems. A 2026 Bifi-94 study adds host-response evidence, not a replacement peak atlas.

The Lys–D-Asx model represents only a subgroup. BaMep D,L-endopeptidase activity was not demonstrated under the 2025 study's conditions.

富含 Lys，但并非纯 Lys 型，Orn 变体并存；Lys 亚群带 β-Asp/β-isoAsn 桥，脱水 MurNAc 丰富。

LC-MS/MS 显示肽干异质性。2026 年 Bifi-94 研究补充宿主反应证据，不构成新的完整峰图。

Lys–D-Asx 模型只代表一个亚群。2025 年研究未在测试条件下证明 BaMep 的 D,L-内肽酶活性。

Predomina Lys, pero coexisten variantes con Orn. El subgrupo Lys presenta puentes β-Asp/β-isoAsn y abundante anhidro-MurNAc.

LC-MS/MS muestra tallos heterogéneos. El estudio Bifi-94 de 2026 aporta respuesta del huésped, no un atlas sustitutivo de picos.

El modelo Lys–D-Asx solo representa un subgrupo. No se demostró actividad D,L-endopeptidasa de BaMep en las condiciones del estudio de 2025.

Sources / 来源 / Fuentes

In silico MS/MS prediction for peptidoglycan profiling uncovers novel anti-inflammatory peptidoglycan fragments of the gut microbiota
Access / 访问 / Acceso: full_text
Locator / 定位 / Localización: Figures 4B, 5 and S8B; Results: Lys/Orn heterogeneity and bridge composition.
Biochemical characterization of Bifidobacterium bifidum peptidoglycan d,l-endopeptidase BbMep that generates NOD2 ligands
Access / 访问 / Acceso: full_text
Locator / 定位 / Localización: Results: BaMep from B. adolescentis ATCC 15703; Figure 2 and Tables S1, S3–S6; lack of demonstrated activity.
Peptidoglycan from Bifidobacterium adolescentis enhances IL-10 production in regulatory B cells to alleviate gut inflammation
Access / 访问 / Acceso: full_text
Locator / 定位 / Localización: Abstract and Results: Bifi-94 host-response and PG biosynthetic-expression evidence; published 9 January 2026.