Peptidoglycan Atlas

Escherichia coli · 4–3

E. coli

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Escherichia coli · 4–3

RodA–PBP2 elongation; FtsW–PBP3/FtsI division; PBP1A/1B also polymerize and crosslink.

Atlas notes

  • Several Mep enzymes cleave both 43 and 33. Carboxypeptidase 45 requires a pentapeptide, and 34 a tetrapeptide. Recycling enzymes have a separate substrate context.

大肠杆菌：主要4→3型

RodA-PBP2伸长；FtsW-PBP3/FtsI分裂；PBP1A/1B辅助聚合交联

图谱说明

  • Mep类中多种酶可切43和33；不能只按D,D/L,D名称推断底物谱。 45示意受体五肽末端；34羧肽酶需要四肽底物，见修剪图。 回收酶另页说明；不能全部当成完整胞壁的周质自溶素。

Escherichia coli · 4–3

Elongación RodA–PBP2; división FtsW–PBP3/FtsI; PBP1A/1B también polimerizan y entrecruzan.

Notas del atlas

  • Varias enzimas Mep cortan 43 y 33. La carboxipeptidasa 45 requiere un pentapéptido y la 34 un tetrapéptido. Las enzimas de reciclaje tienen otro contexto.

Linked enzyme entries / 关联酶条目 / Entradas enzimáticas vinculadas

Cited sources / 引用来源 / Fuentes citadas

  1. R46 Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis of Escherichia coli K12.
  2. R47 Role of endopeptidases in peptidoglycan synthesis mediated by alternative cross-linking enzymes in Escherichia coli.
  3. R64 RodA/SEDS PG polymerase discovery, 2016.
  4. R65 FtsW-bPBP PG polymerase activity, 2019.
  5. R76 Lytic transglycosylase MltG cleaves in nascent peptidoglycan and produces short glycan strands.