Peptidoglycan Atlas

Enterococcus faecalis

E. faecalis

Open interactive atlas / 打开交互图谱 / Abrir atlas interactivo

Enterococcus faecalis

BppA1/BppA2 assemble Ala2 bridges; RodA–PbpA, FtsW–PbpB and aPBPs synthesize PG.

Atlas notes

  • AtlA cleaves G; AtlB/C/E cleave M. Prophage-associated EnpA cleaves the D-Ala–terminal L-Ala junction. Ala2 is typical; Ala2–3 occurs in some reports/strains.

粪肠球菌

BppA1/BppA2：Ala2桥；RodA-PbpA、FtsW-PbpB与aPBP：PG合成

图谱说明

  • AtlA切G；AtlB、AtlC、AtlE切M。 EnpA切供体D-Ala与桥末端L-Ala的连接键；它是前噬菌体相关条目。 Ala2是典型桥；部分文献/菌株报告Ala2-3。

Enterococcus faecalis

BppA1/BppA2 ensamblan puentes Ala2; RodA–PbpA, FtsW–PbpB y aPBP sintetizan PG.

Notas del atlas

  • AtlA corta G; AtlB/C/E cortan M. EnpA, asociada a profago, corta la unión D-Ala–L-Ala terminal. Ala2 es típico; algunas fuentes/cepas presentan Ala2–3.

Linked enzyme entries / 关联酶条目 / Entradas enzimáticas vinculadas

Cited sources / 引用来源 / Fuentes citadas

  1. R11 Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis.
  2. R12 E. faecalis AtlB/AtlC muramidases, 2008.
  3. R13 Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA).
  4. R14 Cleavage specificity of Enterococcus faecalis EnpA (EF1473), a peptidoglycan endopeptidase related to the LytM/lysostaphin family of metallopeptidases.
  5. R15 EnpA from E. faecalis prophage: structural and substrate analysis, 2021.
  6. R20 Pbp4 provides transpeptidase activity to the FtsW-PbpB peptidoglycan synthase to drive cephalosporin resistance in Enterococcus faecalis.