Peptidoglycan Atlas

Enterococcus faecium · D,D

E. faecium

Open interactive atlas / 打开交互图谱 / Abrir atlas interactivo

Enterococcus faecium · D,D

Aslfm adds D-Asp branches; the PBP system, including PBP5, forms 4–3 links.

Atlas notes

  • D-iAsx denotes beta-linked D-Asp/D-isoAsn; amidation varies. SagA cleaves stem D-isoGln2–L-Lys3, not the D-Asx bridge. Nodes simplify atomic connectivity.

屎肠球菌：D,D交联

Aslfm：D-Asp支链；PBP系统（含PBP5）：4→3交联

图谱说明

  • D-iAsx表示β连接D-Asp / D-isoAsn；酰胺化程度不是固定值。 SagA切肽干内部的D-isoGln2-L-Lys3，不直接切D-Asx桥。 保留桥的羧基连接方向；图中残基节点不展开所有原子。

Enterococcus faecium · D,D

Aslfm añade ramas D-Asp; el sistema PBP, incluida PBP5, forma enlaces 4–3.

Notas del atlas

  • D-iAsx indica D-Asp/D-isoAsn unido por beta; la amidación varía. SagA corta D-isoGln2–L-Lys3 del tallo, no el puente D-Asx. Los nodos simplifican los átomos.

Linked enzyme entries / 关联酶条目 / Entradas enzimáticas vinculadas

Cited sources / 引用来源 / Fuentes citadas

  1. R16 Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis.
  2. R17 Aslfm, the D-aspartate ligase responsible for the addition of D-aspartic acid onto the peptidoglycan precursor of Enterococcus faecium.
  3. R18 Acyl acceptor recognition by Enterococcus faecium L,D-transpeptidase Ldtfm.
  4. R21 The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance.