Direct Lys crosslinks · S. suis 31533

Direct Lys crosslinks · S. suis 31533

PBP-mediated D,D-transpeptidation without an additional peptide bridge.

Atlas notes

• Lys-type PG need not contain a bridge. This is structural coverage, not a transferred hydrolase inventory. Unbranched pneumococcal stems share this chemical framework. S. suis 31533 source: Cellosyl/HPLC/MS, D-iGln-containing stems. S. oralis is excluded from a species-wide direct-Lys claim: Uo5 has an L-Ala bridge.

直接交联的 Lys 型 · S. suis 31533

PBP型D,D-transpeptidation；无额外桥肽

图谱说明

• Lys型不一定有额外交联桥。 此页给化学结构定位；没有独立核实的种特异酶不从肺炎链球菌移植。 肺炎链球菌的无桥亚群也可参照此结构，仍需其本身的酶证据。 S. suis 31533 来源为 Cellosyl/HPLC/MS，含 D-iGln 肽干。不可对全部 S. oralis 声称直接 Lys 交联：Uo5 有 L-Ala 桥。

Entrecruzamientos Lys directos · S. suis 31533

Transpeptidación D,D mediada por PBP sin puente peptídico adicional.

Notas del atlas

• El PG tipo Lys no requiere puente. La cobertura es estructural, no un catálogo de hidrolasas transferido. Los tallos neumocócicos sin rama comparten este esquema. S. suis 31533: Cellosyl/HPLC/MS, tallos con D-iGln. No se extiende el modelo Lys directo a toda S. oralis: Uo5 tiene puente L-Ala.

Cited sources / 引用来源 / Fuentes citadas

1. R26 A highly active and negatively charged Streptococcus pyogenes lysin with a rare D-alanyl-L-alanine endopeptidase activity protects mice against streptococcal bacteremia.
2. R131 Significant contribution of the pgdA gene to the virulence of Streptococcus suis
3. R133 Transfer of penicillin resistance from Streptococcus oralis to Streptococcus pneumoniae identifies murE as resistance determinant.