Peptidoglycan Atlas

Mycobacterium · 3–3

M. tuberculosis

Open interactive atlas / 打开交互图谱 / Abrir atlas interactivo

Mycobacterium · 3–3

PBPs form 4–3 links; Ldts form 3–3; NamH participates in MurNAc N-glycolylation.

Atlas notes

  • Both link classes occur, with variable proportions. RipA/B: 23; Ami1: A. Rpf family products are not assigned collectively. CwlM is a regulator, not an A-site enzyme.

分枝杆菌:3→3与特殊修饰

PBP产生4→3;Ldt产生3→3;NamH参与MurNAc N-glycolyl化

图谱说明

  • 图示3→3;实际还存在4→3,比例不是跨生长条件的常数。 RipA/B切23;Ami1切A;Rpf家族不在本版统一确定产物类别。 CwlM是调控因子,不能因酰胺酶样结构域就画A切点。

Mycobacterium · 3–3

Las PBP forman 4–3; las Ldt, 3–3; NamH participa en la N-glicolilación de MurNAc.

Notas del atlas

  • Existen ambos enlaces en proporciones variables. RipA/B: 23; Ami1: A. No se asignan productos a toda la familia Rpf. CwlM es regulador, no enzima del sitio A.

Linked enzyme entries / 关联酶条目 / Entradas enzimáticas vinculadas

  • RipA · M. tuberculosis
  • RipB · M. tuberculosis
  • Ami1 · M. tuberculosis
  • RpfA · M. tuberculosis
  • RpfB · M. tuberculosis
  • RpfC · M. tuberculosis
  • RpfD · M. tuberculosis
  • RpfE · M. tuberculosis

Cited sources / 引用来源 / Fuentes citadas

  1. R43 The peptidoglycan of stationary-phase Mycobacterium tuberculosis predominantly contains cross-links generated by L,D-transpeptidation.
  2. R45 Peptidoglycan Hydrolases RipA and Ami1 Are Critical for Replication and Persistence of Mycobacterium tuberculosis in the Host.
  3. REF0192 N Glycolylation of the nucleotide precursors of peptidoglycan biosynthesis of Mycobacterium spp. is altered by drug treatment.
  4. REF0193 Identification of the namH gene, encoding the hydroxylase responsible for the N-glycolylation of the mycobacterial peptidoglycan.