Peptidoglycan Atlas

Pneumococcus · bridged

S. pneumoniae

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Pneumococcus · bridged

MurM adds Ser or Ala, then MurN adds Ala; FtsW–PBP2x / RodA–PBP2b build PG.

Atlas notes

  • From Lys outward the bridge is Ser–Ala or Ala–Ala. Direct and bridged 4–3 links coexist. PcsB is not assigned a definite bond.

肺炎链球菌:带桥型

MurM先加Ser或Ala、MurN再加Ala;FtsW-PBP2x / RodA-PBP2b

图谱说明

  • 这里从受体Lys向外画Ser→Ala;Ala→Ala也是常见支链。 无桥直接4→3与带桥型并存;不能把每个亚基画成带桥。 PcsB不强行标成已确定的内肽酶切点。

Neumococo · con puente

MurM añade Ser o Ala y MurN añade Ala; FtsW–PBP2x / RodA–PBP2b construyen PG.

Notas del atlas

  • Desde Lys hacia fuera el puente es Ser–Ala o Ala–Ala. Coexisten enlaces 4–3 directos y con puente. PcsB no tiene un enlace definitivo asignado.

Linked enzyme entries / 关联酶条目 / Entradas enzimáticas vinculadas

Cited sources / 引用来源 / Fuentes citadas

  1. R22 Kinetic characterization of lipid II-Ala:alanyl-tRNA ligase (MurN) from Streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates.
  2. R23 Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence.
  3. R24 Structural organization of the major autolysin from Streptococcus pneumoniae.
  4. R25 Pneumococcal PcsB: muralytic activity, exact bond unresolved, 2014.
  5. R74 Purification and polar localization of pneumococcal LytB, a putative endo-beta-N-acetylglucosaminidase: the chain-dispersing murein hydrolase.